A pipeline built on one backbone.
Three lead programs and a set of discovery-stage targets, all running on the Ab-LNP platform. Our selection logic is simple: choose diseases where the pathological cell is identifiable, accessible and worth reprogramming.
Lead programs
HYLG-B1002
Ab-LNP_mRNA- Therapeutic area
- Cardiovascular & metabolic
- Lead indication
- Atherosclerosis
FAP-directed in-situ engineering of modulated vascular smooth muscle cells
Preclinical
HYLG-B1004
Ab-LNP_mRNA- Therapeutic area
- Oncology
- Lead indication
- Colorectal cancer
In-situ programming of tissue-specific pathological cells; protein corona and expression-element optimisation
Preclinical
HYLG-B1010
Ab-LNP_mRNA- Therapeutic area
- Anti-aging
- Lead indication
- Aging prevention
Protection of intestinal barrier integrity against damage
Lead optimization
Discovery programs
Ab-LNP_mRNA · Ab-LNP_CRISPR- Therapeutic area
- Anti-infective, neuro & regenerative medicine
- Lead indication
- Undisclosed
Target and antibody screening across additional cell populations
Discovery
Pipeline information summarises internal development status and is provided for informational purposes only. It is not a clinical claim, an offer, or medical advice. Stages are updated as programs advance.
How a target earns a program.
An identifiable cell
The pathological population must be distinguishable from healthy tissue by a surface marker we can conjugate to.
A payload with a point
The instruction must change the cell in a way that alters disease course — not merely mark it.
A safety story that starts local
If the mechanism depends on systemic exposure to be safe, it is the wrong mechanism for this platform.
A process that transfers
If it cannot be manufactured on the existing backbone, it becomes a new company rather than a new program.
For licensing, co-development and research collaboration enquiries, contact our business development team.
bd@promaxbioscience.cnWe co-develop programs where the cell target is clear.
For licensing, co-development and research collaboration enquiries, contact our business development team.